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Early primary proactive prevention can help reduce or eliminate risk factors, and postpone, avert, or minimize more serious illness, disease, and premature death ( reactive approach is different from proactively preventing, reducing, and/or eliminating risk factors associated with those same diseases

Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R et al

Other than those genes participating in A processing (i.e., APP , PSEN1 and BACE ), several target genes show significant interindividual epigenetic variability in late-onset AD [146]

References Kannan, N