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These probably arent the only causes, but they are well-known contributors to hypothyroidism today

GLP-1 medications were originally designed for diabetes, but some are now FDA-approved for weight management in people who meet certain criteria

Potential Side Effects of Oral GLP-1 and Injectable Semaglutide Nausea or "queasiness" Changes in bowel habits (constipation or diarrhea) Heartburn Since the pill is a daily dose, some patients find the side effects are more consistent throughout the week, whereas the injection can sometimes cause a "peak" of symptoms a day or two after the shot, then improve

Staun-ram E, Goldman S, Gabarin D, et al

Adding the probiotic to a broader metabolic support protocol that includes targeted nutrition changes, regular exercise, and adequate sleep may be necessary to create the cumulative effect that the probiotic alone cannot deliver