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Given the critical role of mitochondria in cellular metabolism and homeostasis, it is imperative to investigate how mitochondrial dysfunction induced by iron overload contributes to disease progression, as well as to explore mitochondrial-related pathways as potential therapeutic targets for various iron overload disorders

In: Feher J (ed) Quantitative human physiology, 2nd edn

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doi: 10.2147/NDT.S407731 67

3.2.1 Pharmacokinetics Geometric mean concentrationtime profiles of plasma cagrilintide appeared to be similar across the four hepatic function groups (Fig