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If the answer to both is no, they will continue to up-titrate the dose by 2.5 mg every 4 weeks until reaching the next weight loss maintenance dose

We reviewed guidelines for the management of type 2 diabetes and obesity management published by the American Diabetes Association, American Association of Clinical Endocrinologists, Obesity Canada, European Association for the Study of Diabetes, and European Association for the Study of Obesity

[1] Rybelsus contains semaglutide, a GLP-1 receptor agonist that mimics the action of naturally occurring incretin hormones

Every participant lost at least 5%, and 63% lost at least 20%

Over half of the participants lost 20% weight, and nearly one in five lost 30% of their body weight