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Athletes lose 800950 mg of sodium per liter of sweat on average, salty sweaters can exceed 2,300 mg/L, and at high exercise intensity total hourly sodium losses reach 1,5001,600 mg

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Figure 4 5.10 Summary of ferroptosis-targeted therapeutic strategies Based on the disease-specific discussions above, ferroptosis-targeted therapeutic strategies can be categorized into three main approaches based on their mechanisms of action: Iron Chelators (e.g., Deferoxamine, Deferiprone) sequester labile iron to limit Fenton chemistry-driven hydroxyl radical generation