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A vial stored in a refrigerator door that opens 15 times per day, under interior LED lighting, in clear glass, is not experiencing the same storage conditions as a vial in the back of the main compartment, wrapped in foil, in a refrigerator that's opened 3 times per day

However, these spikes operate on shorter timescales than the calcium transients and the longer temporal decay of intracellular calcium (on the order of tens of seconds, Fig 3) may be crucial for the negative feedback of the GPCR pathway

Unnikrishnan G, Joy A, Megha M, Kolanthai E, Senthilkumar M

2024;28(12):e18486

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