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The current theoretical framework suggests that this metabolic shift is required to direct the host immune status, and eventually impacts cells and organs that are not directly involved in the immune response (17, 129)

doi: 10.3390/biom13081220 4 Janardhan ReddyYCSundarASNarayanaswamyJCMathSB

J Lab Clin Med 1992

There is a plethora of evidence suggesting that the accumulation of misfolded alpha-synuclein is an integral part of the pathogenic mechanisms in PD (Sian-Hulsmann and Riederer 2021)

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