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Because your cells constantly renew, these results depend on maintenance

Based on our transcriptomic data, all the primary hits of the CRISPR screen ( ABCC1 , SLC30A1 , and SLC39A14 ) are highly expressed in 1321N1 cells (data not shown)

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Instead of paying the full amount upfront, researchers can receive their compounds immediately and spread the cost over time

New basic and clinical research is clarifying the mechanistic relevance and therapeutic feasibility of multiple targets within the glutamate system for novel drug discovery, including NMDA and AMPA (-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors, metabotropic glutamate receptors, and other key regulatory proteins such as glycine transporter 1 and excitatory amino acid transporters