The k cat values of tyramine, dopamine and L -DOPA were reduced 77-fold ( k cat = 0.323 s 1 ), 13-fold ( k cat = 7.36 s 1 ) and 12-fold ( k cat = 9.1 s 1 ), respectively (Table 2)
METs dual role in brain development and immune-gut crosstalk suggests it underpins both core ASD symptoms and systemic comorbidities (e.g., gastrointestinal dysfunction), making it a key node for multi-targeted therapies
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It is generally well-tolerated by patients (305, 307), and clinical trials have demonstrated 100% tolerability and safety (312)
Choosing the Right Therapy for Your Child Choosing the right autism therapy depends on the individuals specific profile their age, developmental level, communication abilities, sensory needs, co-occurring conditions, and family goals
