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The purpose of this review is to summarise the physiological effects as well as the therapeutic implications of the gut hormones glucagon-like peptide-1 (GLP-1), oxyntomodulin, peptide YY (PYY), and glucose-dependent insulinotropic peptide (GIP) in the treatment of obesity and type 2 diabetes

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2.2 Eligibility criteria and relevant outcomes Studies which answered the most important question (regarding the efficacy and safety of subcutaneous semaglutide treatment on weight loss) and report the experiences of adults (age 18 years) with overweight or obese (BMI 25kg/m 2 ) who were prescribed semaglutide treatment for weight management in randomized controlled trials were included

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Helps regulate immunity, mood, and the neuromuscular system