However, these benefits must be balanced with the need to discontinue the drug before pregnancy
Edited by Professor Alessandro Finazzi-Agr Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made
In addition, a portion of synthetic agents have been used clinically to treat various diseases, such as myocardial infarction, heart failure, diabetes, hypertension, tumors, and sepsis
Therefore, particularly for these drugs, frequent updates are essential to accurately assess the drugs long-term benefits
The major plant pathway is different from the animal l-ascorbate synthesis pathway that involves 10 enzymatic steps from d-glucose to l-ascorbate via the intermediate formation of GDP-d-mannose and l-galactose [3] (Figure 1a)
