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Patient Counseling Information Instructions Patients should be informed of the potential risks and benefits of Janumet and of alternative modes of therapy

Thiazolidinediones (e.g., Pioglitazone, Rosiglitazone): Common side effects: Fluid retention, weight gain, increased risk of fractures

Metformin, one of the medicines in dapagliflozin and metformin hydrochloride extended-release tablets, can cause a rare but serious condition called lactic acidosis (a build-up of an acid in the blood) that can cause death

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