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Similar content being viewed by others Main The new generation of obesity medications that target the glucagon-like peptide-1 (GLP-1) receptor and/or the glucose-dependent insulinotropic polypeptide (GIP) receptor are transforming the clinical care of people with obesity and its complications 1

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Shortcomings of Animal Models : While preclinical data can be suggestive, they do not always accurately predict clinical outcomes in humans due to differences in physiology, disease progression, and complex metabolic interactions that cannot be fully replicated in animal models

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