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When Metformin Remains a First-Line Choice Metformin remains the standard initial medication for type 2 diabetes because it is affordable, well-tolerated, has decades of safety data, and addresses insulin resistancethe root driver of many metabolic disorders

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And while lab work isnt required while on a GLP-1, some patients and providers find that blood work provides useful information for tracking progress, monitoring metabolic improvements, and catching any potential issues early on

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