Chemical & physical profile Research code: LY3437943 Class: Triple GIP / GLP-1 / glucagon receptor agonist Molecular formula: C 221 H 343 N 47 O 63 Molecular weight: 4,731.46 g/mol CAS number: 2381089-83-2 Appearance: White to off-white lyophilized powder Purity (HPLC): 99% Plasma half-life (preclinical): ~6 days Storage: 20C lyophilized (24 months)
GRA15, another effector, modulates NF-B signaling through mitochondrial interactions (Rosowski et al., 2011)
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According to a study in Experimental Gerontology, The free radical theory of aging proposes that oxidative stress plays a key role in the aging process
It may be considered as monotherapy if metformin is not suitable, or it may be used in combination with other medications for the treatment of type 2 diabetes