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GHK-Cu modulates the expression of a large number of human genes studies using gene expression microarrays have identified over 4,000 genes whose expression is influenced by GHK-Cu, with effects spanning multiple functional categories including tissue remodeling, antioxidant defense, and growth factor signaling

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For free, unbound copper ions to be present in the cell, an increase in the amount of free copper within the cell would be necessary

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