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It is clear from these findings that while the use of growth factors to treat CNS diseases, such as AD and PD, is a promising strategy, the BBB poses a robust obstacle in turning such strategies into viable treatment options in the clinic

The WHO further notes that obesity significantly increases the risk of cardiovascular disease, stroke and type 2 diabetes, while additional research has linked excess weight to chronic kidney disease and rising healthcare expenditures, creating substantial pressure on healthcare systems globally

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