Acta Clinica Belgica 71(6):407-414, 2016
The IGF1 rs35767 Variant, the IGF-1 LR3 Pathway, and Muscle Growth: What Your Genotype May Mean IGF-1 is a natural growth signal that helps the body build muscle, repair tissue, and support recovery after exercise or injury
As a co-therapy like in case of combined collagen crosslinking (CXL) and intrastromal corneal ring segment (ICRS) implantation to treat keratoconic eyes, no adverse effect from the riboflavin injections were reported (32)
While both IGF-1 LR3 and IGF-1 DES activate the same receptor (IGF1R), their half-lives, delivery methods, and mechanisms of action lead to different safety profiles
A topical peptide is one potential tool, not a complete solution