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Some authors have described AEDG as a pineal-regulating peptide

Accuracy of the PM6 and PM7 methods on bare and thiolate-protected gold nanoclusters

Due to the highly amyloidogenic nature of endogenous human insulin, researchers took inspiration from the proline residues in rat insulin, which are highly homologous but not amyloidogenic (known to disrupt the secondary structure), and incorporated them into the human insulin sequence to develop Pramlintide

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