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To answer the first question, we measured malondialdehyde (MDA) level the product of the brain aldehydic lipid peroxidation and 8-epi Prostaglandin F2 (8-epi PGF2) concentration a marker of oxidative stress and antioxidant deficiency

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Clinical studies show significant improvements in wrinkle depth after 2-4 months of consistent use

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The effects of celastrol mirrored those of Fer-1, a ferroptosis inhibitor, which also reduced iron accumulation and ferroptosis in DKD models