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Furthermore, alanine mutations of the established glutathione-scaffold site residue D90 or of crucial residue K26 in monothiol PfGrx C32S/C88S slowed down the reaction and resulted in linear secondary diagrams for the first rate constant (Fig

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Compared with semaglitude 1 mg, treatment with tirzepatide demonstrated reduced glucagon secretion in response to mixed meal, suggesting an additive effect compared to GPL1 RA on glucagon suppression

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