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However, in the most recent published outcome study TECOS, the authors could show that among patients with T2DM and established cardiovascular disease, sitagliptin did not appear to increase the risk of major adverse cardiovascular events, hospitalization for heart failure, or other adverse events (184)

Dosing, Tolerance, and What to Tell Patients Common dosages range from 100 mg to 300 mg per session , depending on delivery route and clinical indication

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Global identification of modular cullin-RING ligase substrates

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