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Gene expression profiling of dedifferentiated human articular chondrocytes in monolayer culture

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Strong chelators, phosphate-rich buffers and reducing agents in an experimental medium will compete for the copper centre and alter the species actually present

The two peptides appear to address tissue repair through different but potentially complementary pathways BPC-157 through vascularization and growth factor expression, and TB-500 through structural protein regulation and cellular movement

Copper peptides can be used by people with sensitive skin, but the risk of reaction is higher and the reintroduction needs to be slower