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showed that the permeability to the oral administration of 51 Cr-EDTA was increased in patients with small bowel disease and patients with colonic disease

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Direct administration into the CNS One option to efficiently target the brain is via direct administration to the CNS

Since either metformin or GLP-1 analogue has vascular protective effects 7,24 , we reasonably hypothesized that this combination therapy might also have a synergistic protective effect on endothelial function