Unlike dysphoria, anhedonia is characterized more by the lack of feelings than depressed feelings
Roles of specific aminoglycoside-ribosome interactions in the inhibition of translation
IF I LOOK AT THE LAST 10 YEARS OR EVEN 20 YEARS OF MY LIFE, IM LIKE MY GOD LOOK AT ALL THE STUFF I DID, BUT IF I ZOOM IN TO WEEKS MONTHS EVEN SOME YEARS, I FELT LIKE MAKING PROGRESS WAS COMPLETELY INTRACTABLE, AND IT FELT LIKE I WAS YOU KNOW STUCK IN MUD, BUT WHEN YOU KEEP YOUR FEET MOVING, WHEN YOU ZOOM OUT AND YOU KIND OF GET THROUGH THAT SPOT A LOT OF TIMES, YOU REALIZE OH NO I WAS MAKING PROGRESS
Longitudinal human work is scarce
ROXY9 shows a lower reactivity towards GSSG as compared to GRXC2 To elucidate whether the lack of oxidoreductase activity of ROXY9 on HED, Cys-SG and roGFP2 is caused by a different reactivity towards GSH and/or GSSG as compared to class I GRXs, we subjected strep-MBP-ROXY9 and strep-MBP-GRXC2 to different GSH/GSSG molar ratios at p H 7 and monitored their corresponding redox states using the alkylation shift assay as described above