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Mitochondrial H 2 O 2 was also detected by fluorescence microscopy in seeded, intact cells following the green fluorescence emitted by cells transfected with pHyPer-dMito plasmid vector (Evrogen, Moscow, Russia), which express a mitochondrial-tagged H 2 O 2 -sensitive fluorescent probe

It is caused by mutations to the ATP7B gene on chromosome 13

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Nevertheless, these potential effects require further research validation, and no definitive clinical application protocols have been established to date