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Subsequently, Zhongmei Huadong fully transitioned to a biosimilar development pathway, but with clear advantages in clinical data, submission quality, and commercialization capabilities, it remains a strong competitor for the first generic drug

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In a mouse model of Leigh syndrome caused by a deficiency in a component of complex I, the levels of ATP were observed to dictate disease severity and neuronal death 55

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doi: 10.1016/j.bbrc.2007.08.115 18 WiedemannTBielohubyMMllerTDBidlingmaierMPellegataNS