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Walton, P.E., F.R

Sirtuins are known to influence the body's response to oxidative stress and inflammation, and their dysregulation could lead to increased oxidative damage and reduced ATP production (Sara et al., 2021), further exacerbating symptoms of fatigue and metabolic dysfunction

Some studies even suggest the combination may influence metabolic function or appetite control in women with PCOS

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GLP-1RAs (and their offshoots that add agonists of other key metabolic regulation substances) have shown particular promise in patients with obesity-related cardiovascular and metabolic complications, offering synergistic benefits that extend beyond weight loss