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Absolute Contraindications Do not use GLP-1 and dual GIP/GLP-1 medications if you have any of the following: A personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) A history of pancreatitis or symptomatic gastroparesis Severe gastrointestinal disease Pregnant or planning pregnancy Final Thoughts GLP1 and dual GIP/GLP1 receptor are now widely used to help manage type 2 diabetes and obesity

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However, most studies were conducted for a short time on small groups of individuals, often without a control group (135)

At room temperature, lyophilized peptides remain stable for several weeks, but for long-term storage it is best to keep them frozen at 20 C (4 F) or below

3.3 GLP-1 RAs and MASLD Twenty-four meta-analyses primarily examined the efficacy of GLP-1 RAs in MASLD from the five aspects mentioned above