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Also anyone with known environmental exposures, a history of amalgam fillings, high fish consumption, or occupational heavy metal contact

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Diarrhea or Constipation: Gastrointestinal disturbances are frequently reported

A cloudy solution, visible particles, or discoloration after 5 minutes of gentle swirling is widely flagged as a sign of degraded peptide

This varies dramatically by peptide and by the aspect of disease being targeted: Anti-inflammatory effects (KPV, BPC-157): Often noticeable within days to 2 weeks Gut healing (BPC-157, KPV): Initial improvements in 1-2 weeks, more substantial healing over 4-8 weeks Immune rebalancing (thymosin alpha-1): Treg expansion takes weeks to months