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3.8 Expression distribution of representative ferroptosis-promoting and ferroptosis-suppressing signature genes in renal cells of healthy individuals and disease states In mechanistic investigations of ferroptosis-driven kidney diseases, the GSE183279 single-cell dataset provides critical insights into the cell type-specific expression and disease-dependent regulation of ferroptosis-promoting signature genes

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In studies in adults with obesity, the percentage of patients losing at least 10% of their body weight were 19% (taking the 3.75 mg/23 mg dose) and 47% (taking the 15 mg/92 mg dose), compared to 7% of those taking a placebo

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Thakurta RG, Singh OP, Bhattacharya A, Mallick AK, Ray P, Sen S, Das R