Tayran H, Yilmaz E, Bhattarai P et al (2024a) ABCA7dependent neuropeptideY signalling is a resilience mechanism required for synaptic integrity in Alzheimers disease
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Figure 8 Discussion GLP-1 agonists belong to the family of G proteins that couple with intracellular pathways to increase cyclic adenosine monophosphate to decrease glucagon release, enhance insulin secretion, enhance satiety, and decrease gastric emptying ( In the present study, we found a reduction in the total daily insulin dose and HbA1c following the use of GLP-1 agonists as additional therapy to insulin, 2.21, 95% CI (0.433.98), and SMD, 0.23, 95% CI (0.140.32), respectively
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Other medications with effects on sodium channels, such as gabapentinoids and baclofen, are also commonly used, though there is inconsistent evidence on the efficacy of gabapentin for cramps in ALS [181]
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