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When IGF-1 axis is activated, multiple signaling pathways corresponding to its kinase domain are also activated, including PI3K/Akt pathway and Raf/MEK/ERK level linkage pathway, which can ultimately reduce IR and prevent cell apoptosis (58, 59), thereby improving NAFLD
While the potential of tripeptides in biomedical applications has been proven significant, challenges such as stability, bioavailability, and immunogenicity need to be addressed
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Studies in rodents show accelerated healing of tendons (including the Achilles and patellar tendons), ligaments, muscle tissue, bone, and gut mucosa
The statistical test showed evidence of a publication bias for HbA1c ( = 0.027, = 0.129
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