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#Glucagn #Metabolismo Mecanismos de Accin a Nivel Central Regulacin del apetito y la ingesta alimentaria El GLP-1 acta en el hipotlamo para reducir el apetito , lo que conduce a una menor ingesta calrica y, en consecuencia, a la prdida de peso

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For example, muscle mass shows only a small reduction by muscle-specific single deletion of either IR or IGF1R, but is markedly decreased by muscle-specific deletion of both IR and IGF1R (47)

Proc Natl Acad Sci U S A 117(34):2087420880 Cai J et al (2023) AgRP neurons are not indispensable for body weight maintenance in adult mice