As summarized in Table S1, the level of evidence is still low, derived mainly from in vitro studies, animal models, and small patient cohorts, with only limited data from RCT available
However, those with existing gallstones need extra vigilance, particularly during the first 20 weeks when risk may be higher based on trial observations
Wegovy is FDA-approved to: Manage weight in adults and children ages 12+ with obesity (BMI of 30+) and in adults with overweight with at least one weight-related medical condition (e.g
While reducing acid can be helpful for these conditions, it may also impact how other medications are absorbed, especially those that rely on stomach acid to enter the bloodstream effectively
What leads to significant weight loss for one individual might result in minimal changes for another