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That selectivity is the reason it is paired with Tesamorelin rather than an older, dirtier secretagogue

While CJC-1295, Ipamorelin, Sermorelin, and IGF-1 LR3 are often grouped together, they actually work at different points along the body's natural Growth Hormone (GH) and Insulin-Like Growth Factor-1 (IGF-1) pathway

Clinical oversight required: Dosage adjustments, reconstitution, and injection technique should always be guided by a licensed provider

How ipamorelin and CJC-1295 are thought to work To understand these peptides, it helps to start with the axis they act on

CJC-1295 is modified (the version used in our clinic is CJC-1295 without DAC) to extend that signal, keeping the GHRH stimulus present long enough for a meaningful pulse of growth hormone to occur