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The STEP 1 trial revealed a mean weight loss of 14.9% over 68 weeks in non-diabetic participants

The Side Effect Showdown: A Head-to-Head Comparison Table To make this easier to visualize, heres a simplified breakdown based on the major clinical trial data available as of 2026

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Int J Mol Sci 25:2760

Melanotan 2 activates multiple melanocortin receptors and shows a wider range of responses