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Yohimbe, for example, is often promoted for improving erectile dysfunction (ED), enhancing athletic performance, treating high blood pressure, and more

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Mitochondrial and Immune Function Healthy mitochondrial function depends on maintaining an appropriate balance between energy production and oxidative stress

However, further dose-response analysis and adjustment for intake of other vitamin and mineral supplements indicated that all-cause mortality risk was significantly increased by 7% only at a dose of 2,000 IU/day, which is notably higher than the UL for adults (1,100 IU/day of synthetic tocopherol or 1,500 IU/day of natural tocopherol)