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The major allergen in the HDM extract, Der f2 (Johannessen et al., 2005), induced the production of proinflammatory cytokines, which was mediated by toll-like receptor 4

HSDD affects roughly 1 in 10 adult women in the United States

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Inclusion criteria were age 18 years, BMI of 2535 kg/m 2 , prediabetes (impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT)) using the American Diabetes Association criteria [17] and a stable body weight for 3 months prior to the study

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