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Relevant preclinical studies have demonstrated that Ex-4, by acting on GLP-1R, inhibits the PI3K/Akt signaling pathway and increases the expression of Caspase-3 and E-cadherin, thereby promoting apoptosis in human ovarian cancer cells and reducing their metastasis [72]

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PLoS One 17 , 0264413

GSH plays roles in detoxifying toxic compounds, protein folding, the regeneration of vitamins C and E, maintenance of mitochondrial function, antiviral defense, the regulation of cellular proliferation, apoptosis, and the immune response

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