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This finding is also supported by several genetic variations seen in ASD patients related to the transmethylation/transsulfuration pathway where glutathione is one of the byproducts (James et al., 2004, 2006, 2008)

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however, increased ischemic stroke risk in this context has been observed as well (Chen 2020

Outlook toward biomarker-driven ferroptosis therapies A central challenge and opportunity will be to define which tumors are truly CoQoxidoreductase dependent in vivo