semaglutide and pantoprazole DANGEROUS SIDE EFFECTS OF What other medications can be

So, it's not a skincare product

Short-chain fatty acids (SCFAs) such as butyrate, a bacterial metabolite produced from dietary fibre, can directly trigger GLP-1 release by binding to the membrane receptor GPR43 ( Both preclinical and clinical studies have demonstrated that GLP-1s modulate the gut microbiota composition by delaying gastric emptying and altering luminal glucose ( Firmicutes Lachnospiraceae and Clostridiales ), alongside an increase in Proteobacteria (e.g., Burkholderiales bacterium YL45 ) and Akkermansia muciniphila a species largely associated with high-fibre diets and mucosal barrier health (69 Firmicutes/Bacteroidetes ratio and an increase in Prevotella , species that have been linked to lower inflammation ( Firmicutes/Bacteroidetes ratio was observed ( The findings concerning human gut microbiota remain controversial

Continued use is often necessary to maintain weight loss, as discontinuation of the medication can lead to weight regain

doi: 10.1146/annurev-immunol-040210-092915 63 CamineroAMeiselMJabriBVerduEF

Keep an eye on how you feel and report any side effects that get worse or don't go away