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(AP Photo/Seth Wenig) Puerto Rico and Carlos Beltran supporters pose for pictures with a Puerto Rican flag before the start of the Baseball Hall of Fame induction ceremony in Cooperstown, N.Y., Sunday, July 26, 2026

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Ozempic (semaglutide) Disease area(s): Metabolic diseases Manufacturer(s): Novo Nordisk 2024 Sales (USD): $17.45 billion Why it sold so well: Novo Nordisks GLP-1 blockbuster for type 2 diabetes continued its impressive growth in 2024, with sales increasing by 26% year-over-year to DKK 120.3 billion ($17.45 billion)

For injectable semaglutide, doses start at 0.25 mg per week and may increase to a maximum of 2 mg (Ozempic) or 2.4 mg (Wegovy) weekly. For oral semaglutide (Rybelsus), doses start at 3 mg daily and increase to a maximum of 14 mg