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Progress towards therapies for disease modification in Parkinsons disease

Structurally unique GLP-1-based medicines that achieve substantially greater and rapid weight loss may impact musculoskeletal health, providing a rationale for therapeutics that more selectively target adipose tissue loss while preserving muscle mass and strength

ShtyrlinYGPetukhovAStrelnikAShtyrlinNIksanovaAPugachevMet al

They Might Reduce the Alcohol Buzz Researchers found that adults taking GLP-1 weight-loss drugs, including semaglutide medications, showed a slower rise in blood alcohol levels and reported feeling less intoxicated compared to those not on the drugs

As an important regulator of Wnt transduction in the canonical signaling pathway in tumours, Dickkopf-related protein 3 (DKK3) negatively regulates aerobic glycolysis [HK2, HIF-1, GLUT-1, LDHA and 3-phosphoinositide-dependent protein kinase-1 (PDK-1)] in BxPC-3 cells