The calculator handles this automatically: you enter the mg quantity of the vial and the volume of bacteriostatic water, and the tool does the math
Canapp SO Jr, Farese JP, Schultz GS, et al
Studies show that while GHRP-2 and GHRP-6 administration resulted in increased plasma levels of ACTH and cortisol, ipamorelin did not release ACTH or cortisol at levels significantly different from those observed following growth hormone-releasing hormone (GHRH) stimulation
Interestingly, this effect seems to be mediated through hepatic glucagon signalling, as infusion into the portal vein induced a satiating response whereas infusion into the inferior vena cava did not (64)
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