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All samples were collected under Institutional Review Board-approved protocols (STUDY61977 and STUDY7108), and all participants provided written informed consent

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The GC column was 5% phenyl and the temperature ramp ranged from 40 to 300 C in a 16 minute period

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Patients were also instructed to avoid the use of tranexamic acid (topical or oral) and to refrain from undergoing any other form of phototherapy during the entire study period