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"So, these drugs have side effects." Roche buys Telavant from Roivant for $7 billion, gaining bowel disease drug candidate Roche said Monday it was buying Telavant Holdings for $7.1 billion upfront, picking up a promising experimental therapy for inflammatory bowel diseases.Telavant is owned by Roivant Sciences, with Pfizer holding a minority stake

Because of the defined role of GST in drug metabolism, elevated expression of GSTP1 in solid tumors or in drug-resistant cells has been associated frequently with detoxification reactions even in instances where there is no evidence that the selecting drug is a substrate for GSTP1

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