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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for managing type 2 diabetes and chronic weight management

[ 3 ] Variations in species studied, routes of administration, dosing regimens, and experimental methodologies likely contributed to these conflicting results

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Notably, metabolic benefits often diminish after treatment discontinuation [116], underscoring the importance of long-term planning in therapeutic decision-making