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Harmful hydrogen peroxide cellular levels are minimized by the enzyme glutathione peroxidase (GP) using GSH as a reductant
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
One potential mechanism is the Nrf2-ARE pathway, which induces a phase 2 detoxification response that promotes disruption of Nrf2-Keap protein interactions, translocation of Nrf2 to the nucleus, and regulation of target gene expression through the ARE, enhancing cellular defense against oxidative damage (Lau et al., 2008)
Vitamin C (5001,000 mg) helps recycle oxidized GSSG back to active GSH
Is it time to reevaluate methyl balance in humans
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