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While we cannot disregard the possibility of some remaining effects of relaxation time differentials, we note that our results are metabolite-specific, while systematic between-group differences in relaxation times would likely impact all metabolite concentrations equally

Figure 5 During starvation-induced autophagy, TBK1 can positively and negatively regulate autophagic flux by inhibiting or activating mTORC1 respectively (173, 174)

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Other processes that require ascorbic acid include biosynthesis of corticosteroids and aldosterone, proteins, neuropeptides, and carnitine

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